ESR1
estrogen receptor 1
别名:
ER, ESR, ESRA, ESTRR, Era, NR3A1
物种:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), Goat ESR1 (100860768), sheep ESR1 (443228), domestic guinea pig Esr1 (100713276), Zebrafish esr1 (259252), dog ESR1 (403640), cow ESR1 (407238), Horse ESR1 (791249) ...展开
UniProtKB ID:
基因ID:
- Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
- Mouse(13982) estrogen receptor 1 (alpha)
- Rat(24890) estrogen receptor 1
- Goat(100860768) estrogen receptor 1
- sheep(443228) estrogen receptor 1
- domestic guinea pig(100713276) estrogen receptor 1
- Zebrafish(259252) estrogen receptor 1
- dog(403640) estrogen receptor 1
- cow(407238) estrogen receptor 1
- Horse(791249) estrogen receptor 1
- domestic cat(552888) estrogen receptor 1
- chicken(396099) estrogen receptor 1
- Thale Cress(837856) ethylene-responsive transcription factor ESR1
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Small Molecule - Activator
Small Molecule - Agonist
货号
说明
物种
17β-雌二醇 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
雌酚酮 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Small Molecule - Allosteric Modulator
货号
说明
物种
泰莫西芬, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
物种
human
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-ESR1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
抗雌激素相关受体α抗体, Upstate®, from rabbit,
物种反应性
hamster, human, mouse, rat
应用
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-ESR1 (Ab-106) 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Small Molecule - Mixed Agonist/Antagonist
Proteins
货号
说明
物种
雌激素受体-α 人, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
物种
human
esiRNA
货号
说明
物种