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Merck

CHRM4

cholinergic receptor, muscarinic 4

别名:
HM4, M4R
物种:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), chicken CHRM4 (423195), cow CHRM4 (512928), domestic cat CHRM4 (101088360), dog CHRM4 (611314), sheep CHRM4 (101114554), Domestic Rabbit CHRM4 (100008791), domestic guinea pig Chrm4 (100714736)
UniProtKB ID:
P08173, B2RPP4, Q0VD60, Q4VBK7
基因ID:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

货号
说明
物种
P6503
毛果芸香碱 盐酸盐, ≥99% (titration), powder,
物种
human
A2251
乙酰基-β-氯化甲基胆碱, ≥98% (TLC), powder,
物种
human
P6628
毛果芸香碱 硝酸盐, ≥98% (HPLC),
物种
human
O100
氧化震颤素M, solid,
物种
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
物种
human

Small Molecule - Antagonist

货号
说明
物种
B1390
比沙可啶, analytical standard, for drug analysis,
物种
human
T9778
托吡卡胺, solid,
物种
human
S1875
(-)-东莨菪碱 氢溴酸盐 三水合物, ≥98% (HPLC), powder,
物种
human
A0257
阿托品 硫酸盐 一水合物, ≥97% (TLC), crystalline,
物种
human
S7882
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
ZMS1165
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
ELISA
affinity binding assay
immunocytochemistry
western blot
SAB4300824
Anti-CHRM4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
A8404
盐酸阿米替林 盐酸盐, ≥98% (TLC), powder,
物种
human
D4526
多塞平 盐酸盐, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
物种
human
51330
骆驼蓬灵, ≥95%,
物种
human, rat

Small Molecule - Ligand

货号
说明
物种
A138
Aminobenztropine, solid,
物种
human

esiRNA

货号
说明
物种
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
物种
mouse