APP
amyloid beta (A4) precursor protein
别名:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
物种:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), domestic cat APP (101085564), cow APP (280722), dog APP (403407), naked mole-rat App (101724743), domestic guinea pig App (100715302)
UniProtKB ID:
基因ID:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
货号
说明
物种
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
抗APP A4抗体，a.a.APP{NT}的66-81，克隆22C11, clone 22C11, Chemicon®, from mouse,
物种反应性
canine, fish, human, monkey, mouse, pig, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-β淀粉样蛋白抗体，小鼠单克隆 小鼠抗, clone NAB 228, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anti-APP Antibody, clone 1F22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-淀粉样蛋白β42抗体，克隆G2-11, clone G2-11, from mouse,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗淀粉样蛋白抗体，β1-40, Chemicon®, from rabbit,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot