1555005

Prednisolone

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione, 1-Dehydrocortisol, 1-Dehydrohydrocortisone, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione
• Empirical Formula (Hill Notation): C₂₁H₂₈O₅
• CAS Number: 50-24-8
• Molecular Weight: 360.44
• Beilstein: 1354103
• MDL number: MFCD00003649
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750934

Properties

• grade: pharmaceutical primary standard
• API family: prednisolone
• manufacturer/tradename: USP
• mp: 240 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1
• InChI: 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: OIGNJSKKLXVSLS-VWUMJDOOSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

It is intended to be used as a USP reference standard in specified quality tests and assays.
Also used to prepare standard and system suitability solutions as described in the following United States Pharmacopeia (USP) monographs:

• Prednisolone
• Prednisolone Compounded Oral Suspension, Veterinary
• Prednisolone Sodium Phosphate
• Dexamethasone Oral Solution
• Tetracycline Hydrochloride, Novobiocin Sodium, and Prednisolone Tablets
• Prednisolone Oral Solution
• Prednisolone Tablets
• Prednisolone Sodium Phosphate Injection
• Prednisolone Sodium Phosphate Ophthalmic Solution
• Hydrocortisone Gel
  

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H360FD
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable