1134368

Citric acid

United States Pharmacopeia (USP) Reference Standard

• Linear Formula: HOC(COOH)(CH₂COOH)₂
• CAS Number: 77-92-9
• Molecular Weight: 192.12
• Beilstein: 782061
• MDL number: MFCD00011669
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749410
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard (unable to validate for USP)
• API family: citric acid
• expl. lim.: 8 %, 65 °F
• manufacturer/tradename: USP
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• mp: 153-159 °C (lit.)
• solubility: water: 383 g/L at 25 °C
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC(=O)CC(O)(CC(O)=O)C(O)=O
• InChI: 1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChI key: KRKNYBCHXYNGOX-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard solutions to test the limit of citric acid according to the following United States Pharmacopeia (USP) monographs:

• Powdered Garcinia Hydroxycitrate Extract
• Calcium Citrate Malate
• Anticoagulant Citrate Phosphate Dextrose Adenine Solution
• Magnesium Carbonate, Citric Acid, and Potassium Citrate for Oral Solution
• Monoglyceride Citrate
• Anticoagulant Sodium Citrate Solution
• Tricitrates Oral Solution
• Anticoagulant Citrate Phosphate Dextrose Solution
• Cranberry Liquid Preparation
  

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable