T0625
Taurine
≥99%
Synonym(s):
2-Aminoethanesulfonic acid
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About This Item
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Product Name
Taurine, ≥99%
biological source
synthetic
Quality Level
Assay
≥99%
form
powder
color
white
mp
>300 °C (lit.)
application(s)
cell analysis
storage temp.
room temp
SMILES string
NCCS(O)(=O)=O
InChI
1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
InChI key
XOAAWQZATWQOTB-UHFFFAOYSA-N
Gene Information
human ... GRIN1(2902)
rat ... Ppm1a(24666)
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General description
Taurine (2-aminoethanesulphonic acid) is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys.
Application
Taurine has been used for the isolation and growth of taurine-utilizing purple non-sulfur bacteria and in phototrophic growth experiments.
Biochem/physiol Actions
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine modulates the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. It also has a role in bile formation and fat digestion. Deficiency of taurine is associated with anxiety, hyperactivity, epilepsy and depression.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides.
Microbiology, 150(Pt 6), 1881-1891 (2004)
The potential health benefits of taurine in cardiovascular disease.
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
Hepatology (Baltimore, Md.), 31(6), 1305-1312 (2000-05-29)
The biosynthesis of bile acids by primary cultures of normal human hepatocytes has been investigated. A general and sensitive method for the isolation and analysis of sterols and bile acids was used, based on anion exchange chromatography and gas chromatography-mass
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
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Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as
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