SML2308

Atazanavir sulfate

≥95% (HPLC)

• Synonym(s): (3S,8S,9S,12S)-1,14-Dimethyl-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate sulfate
• Empirical Formula (Hill Notation): C₃₈H₅₂N₆O₇ · H₂SO₄
• CAS Number: 229975-97-7
• Molecular Weight: 802.93
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥95% (HPLC)
• form: powder
• optical activity: [α]/D -40 to -50°, c = 1 in methanol: water (1:1)
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• shipped in: wet ice
• storage temp.: 2-8°C
• SMILES string: O[C@@H](CN(CC1=CC=C(C2=CC=CC=N2)C=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)[C@@H](NC([C@@H](NC(OC)=O)C(C)(C)C)=O)CC3=CC=CC=C3.O=S(O)OO
• InChI: 1S/C38H52N6O7.H2O4S/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28;1-5(2,3)4/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47);(H2,1,2,3,4)/t29-,30-,31+,32+;/m0./s1
• InChI key: DQSGVVGOPRWTKI-QVFAWCHISA-N

Description

Biochem/physiol Actions

Antiviral HIV Protease Inhibitor

Atazanavir sulfate is the prodrug of Atazanavir, an antiviral HIV protease inhibitor.

Safety Information

• Pictograms: GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H318,H372
• Precautionary Statements: P260 - P264 - P270 - P280 - P305 + P351 + P338 - P314
• Hazard Classifications: Eye Dam. 1 - STOT RE 1
• Target Organs: Heart,Liver
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable