SCP0003
Proteasome Substrate 1, fluorogenic
≥95% (HPLC), lyophilized
Synonym(s):
Z-LLL-AMC, Z-Leu-Leu-Leu-AMC
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About This Item
Empirical Formula (Hill Notation):
C36H48N4O7
Molecular Weight:
648.79
UNSPSC Code:
12352200
NACRES:
NA.32
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product name
Proteasome Substrate 1, fluorogenic,
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥80%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Z-Leu-Leu-Leu-AMC
Biochem/physiol Actions
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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S Tsubuki et al.
Biochemical and biophysical research communications, 196(3), 1195-1201 (1993-11-15)
A tripeptide aldehyde protease inhibitor, benzyloxycarbonyl(Z)-Leu-Leu-leucinal (ZLLLa1), initiates neurite outgrowth in PC12 cells at an optimal concentration of 30nM. This result suggests the existence of a protease which regulates neurite formation in PC12 cells. We report here an attempt to
Oriane Tasta et al.
Free radical biology & medicine, 164, 303-314 (2021-01-16)
Premature placental senescence is a hallmark of pregnancy-related disorders such as intrauterine growth restriction (IUGR) and preeclampsia (PE), two major cause of maternal and neonatal morbidity and mortality. Oxidative stress and lipid peroxidation are involved in the pathogenesis of PE
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