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Key Documents

R9629

Sigma-Aldrich

D-(−)-Ribose

suitable for cell culture, BioReagent

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
Molecular Weight:
150.13
Beilstein:
1723081
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.75

biological source

microbial

product line

BioReagent

Assay

≥99% (GC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

88-92 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

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Application

D-(−)-Ribose has been used for microtissue fabrication and in cell culture.

Biochem/physiol Actions

Ribose is an aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. Ribose-5-phosphate supports the biosynthesis of tryptophan and histidine and is a component of the pentose phosphate pathway.

Suitability

This D-ribose has been qualified for use as a supplement in cell culture.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Schnupf P, et al.
Nature, 520(7545), 99-100 (2015)
Matthew Walker et al.
Scientific reports, 10(1), 7696-7696 (2020-05-08)
When stretched, cells cultured on 2D substrates share a universal softening and fluidization response that arises from poorly understood remodeling of well-conserved cytoskeletal elements. It is known, however, that the structure and distribution of the cytoskeleton is profoundly influenced by

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