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Key Documents

PRS2301

Sigma-Aldrich

Anti-AIF antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Connector enhancer of kinase suppressor of Ras 1

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About This Item

MDL number:
MFCD02685955
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 67 kDa

species reactivity

mouse, human, rat

technique(s)

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q969H4

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CNKSR1(10256)

General description

The previously assigned protein identifier O95381 has been merged into Q969H4. Full details can be found on the UniProt database.

Immunogen

a peptide corresponding to amino acids 593-606 of human AIF. This sequence is identical to mouse and rat AIF.

Linkage

The action of this antibody can be blocked using blocking peptide SBP2301.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xiaowan Wang et al.
International journal of molecular sciences, 15(11), 20449-20468 (2014-11-12)
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NAD+ is a cofactor required for glycolysis, tricarboxylic acid cycle, and complex I enzymatic reaction. In mammalian cells, NAD+ is predominantly synthesized through the salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme. Previously, we demonstrated that NAMPT exerts
Roberta L Turner et al.
Virology, 456-457, 205-219 (2014-06-04)
Adenovirus inundates the productively infected cell with linear, double-stranded DNA and an abundance of single-stranded DNA. The cellular response to this stimulus is antagonized by the adenoviral E1B and E4 early genes. A mutant group C adenovirus that fails to
Dénes Nagy et al.
Archives of dermatological research, 306(10), 885-902 (2014-10-17)
TASK-3 (KCNK9 or K2P9.1) channels are thought to promote proliferation and/or survival of malignantly transformed cells, most likely by increasing their hypoxia tolerance. Based on our previous results that suggested mitochondrial expression of TASK-3 channels, we hypothesized that TASK-3 channels
Shengqiang Xu et al.
PloS one, 9(7), e100824-e100824 (2014-07-06)
Apoptosis-inducing factor (AIF) plays a crucial role in caspase-independent programmed cell death by triggering chromatin condensation and DNA fragmentation. Therefore, it might be involved in cell homeostasis and tumor development. In this study, we report significant AIF downregulation in the
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