H3035

Hydrocortisone 21-acetate

meets USP testing specifications

• Synonym(s): 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate, 17-α-Hydroxycorticosterone acetate, 17-Hydroxycorticosterone 21-acetate, 21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione, 4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate
• Empirical Formula (Hill Notation): C₂₃H₃₂O₆
• CAS Number: 50-03-3
• Molecular Weight: 404.50
• Beilstein: 2066841
• EC Number: 200-004-4
• MDL number: MFCD00037714
• UNSPSC Code: 41116107
• PubChem Substance ID: 24895547
• NACRES: NA.21

Properties

• Agency: USP/NF; meets USP testing specifications
• mp: 223 °C (dec.) (lit.)
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
• InChI key: ALEXXDVDDISNDU-JZYPGELDSA-N
• Gene Information: human ... NR3C1(2908) , SERPINA6(866)

Description

Application

Hydrocortisone 21-acetate is used as a stabilized form of the glucocorticoid in studies on stress and homeostasis.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H360Df,H373
• Precautionary Statements: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves