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G6526

Sigma-Aldrich

D-Glucose 6-phosphate potassium salt

≥95% anhydrous basis (enzymatic)

Synonym(s):

D(+)-Glucopyranose 6-phosphate potassium salt, Robison ester

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About This Item

Linear Formula:
C6H12O9PK
CAS Number:
Molecular Weight:
298.23
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

Assay

≥95% anhydrous basis (enzymatic)

form

powder

color

white

solubility

water: 50 mg/mL, clear to hazy, colorless

cation traces

K: 10.16-15.88% (ICP anhydrous)

storage temp.

−20°C

SMILES string

[K].OC1OC(COP(O)(O)=O)C(O)C(O)C1O

InChI

1S/C6H13O9P.K.H/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;/h2-10H,1H2,(H2,11,12,13);;

InChI key

UTZCQRPSJJQUEE-UHFFFAOYSA-N

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Application

Treatment of rat pancreatic islets with the glucose metabolite D-glucose 6-phosphate elevates the level of ATP-dependent Ca2+ within the endoplasmic reticulum indicating it is a key regulator of Ca2+ storage in the islets.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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B A Wolf et al.
The Journal of biological chemistry, 261(35), 16284-16287 (1986-12-15)
Glucose stimulation of islets is coupled with the rapid intracellular release of myo-inositol 1,4,5-trisphosphate (IP3) and arachidonic acid which in turn mobilize Ca2+ stored in the endoplasmic reticulum (ER). The metabolism of glucose is required for insulin secretion although the

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Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.

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