Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

D8399

Sigma-Aldrich

Danazol

≥98% (TLC), powder, androgen receptor agonist

Synonym(s):

17β-Hydroxy-2,4,17α-pregnadien-20-yno[2,3-d]isoxazole, 2,4,17α-Pregnadien-20-yno[2,3-d]­isoxa­zol-17-ol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H27NO2
CAS Number:
17230-88-5
Molecular Weight:
337.46
EC Number:
241-270-1
MDL number:
MFCD00056838
UNSPSC Code:
51111800
PubChem Substance ID:
24277708
NACRES:
NA.77

product name

Danazol, ≥98%

Assay

≥98%

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

originator

Sanofi Aventis

SMILES string

CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C

InChI

1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1

InChI key

POZRVZJJTULAOH-ZIKCMSSPSA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Danazol is a weak androgen; anterior pituitary suppressant.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H312 + H332,H361

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

H Beaumont et al.
The Cochrane database of systematic reviews, (3)(3), CD001017-CD001017 (2007-07-20)
Heavy menstrual bleeding (HMB) is an important cause of ill health in pre menopausal women. Medical therapy, with the avoidance of possibly unnecessary surgery is an attractive treatment option, but there is considerable variation in practice and uncertainty about the
Johannes Parmentier et al.
International journal of pharmaceutics, 437(1-2), 253-263 (2012-09-04)
Liposomes are generally well tolerated drug delivery systems with a potential use for the oral route. However, little is known about the fate of liposomes during exposure to the conditions in the gastro-intestinal tract (GIT). To gain a better understanding
Maria Vertzoni et al.
Molecular pharmaceutics, 9(5), 1189-1198 (2012-04-10)
The first aim of this study was to characterize the luminal contents and their micellar phase after the administration of a heterogeneous liquid meal to healthy adults. The second aim was to evaluate the impact of micellar lipids and coarse
Gregory W Thomas et al.
Biochemical and biophysical research communications, 421(4), 707-712 (2012-05-01)
Breakdown of endothelial barrier function is a hallmark event across a variety of pathologies such as inflammation, cancer, and diabetes. It has also been appreciated that steroid hormones impart direct biological activity on endothelial cells at many levels. The purpose
Ravi Devraj et al.
International journal of pharmaceutics, 441(1-2), 323-333 (2012-11-28)
In vitro digestion testing is of practical importance to predict the fate of drugs administered in lipid-based delivery systems. Calcium ions are often added to digestion media to increase the extent of digestion of long-chain triglycerides (LCTs), but the effects
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service