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93759

Sigma-Aldrich

Pyridoxal hydrochloride

≥99.5% (T)

Synonym(s):

3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde hydrochloride, PL HCl

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About This Item

Empirical Formula (Hill Notation):
C8H9NO3 · HCl
CAS Number:
Molecular Weight:
203.62
Beilstein:
3656994
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.79

biological source

synthetic

Assay

≥99.5% (T)

form

powder

loss

≤0.6% loss on drying

color

white to faint beige

mp

173 °C (dec.) (lit.)

anion traces

sulfate (SO42-): ≤1000 mg/kg

cation traces

Ca: ≤250 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤15 mg/kg
Cu: ≤5 mg/kg
Fe: ≤15 mg/L
K: ≤50 mg/kg
Mg: ≤10 mg/kg
Mn: ≤100 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

cell analysis

SMILES string

Cl[H].[H]C(=O)c1c(CO)cnc(C)c1O

InChI

1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H

InChI key

FCHXJFJNDJXENQ-UHFFFAOYSA-N

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General description

Pyridoxal is a derivative of vitamin B6. Vitamin B6 derivatives contain a core pyridine ring. Pyridoxal consists of an aldehyde group at pyridine′s 4′ position. Pyridoxal is a water-soluble vitamin.

Application

For the labeling of amino acids and their detection in picomolar amounts; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate

Biochem/physiol Actions

Vitamin B6 derivatives are initially oxidized to pyridoxal. It is then phosphorylated to pyridoxal 5′- phosphate (P5P). Pyridoxal 5′- phosphate is the circulatory form of vitamin B6.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of water-soluble vitamins in infant milk by high-performance liquid chromatography
Albala S, et al.
Journal of Chromatography A, 778(1-2), 247-253 (1997)
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Journal of the American Chemical Society, 131(38), 13659-13667 (2009-09-10)
CW EPR spectra of reduced [2Fe-2S](Cys)(3)(His)(1) clusters of mammalian mitoNEET soluble domain appear to produce features resulting from the interaction of the electron spins of the two adjacent clusters, which can be explained by employing the local spin model. This
Vitamin B6 (Pyridoxine; Pyridoxal 5'-Phosphate)
CH, C
Alternative Medicine Review, 6(1), 87-87 (2001)
Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)
Lucia Carrano et al.
BioMed research international, 2015, 419383-419383 (2015-09-09)
With the increasing need of effective antibiotics against multi-drug resistant pathogens, lantibiotics are an attractive option of a new class of molecules. They are ribosomally synthetized and posttranslationally modified peptides possessing potent antimicrobial activity against aerobic and anaerobic Gram-positive pathogens

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