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Y0000401

Pimobendan for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Pimobendan, 4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl-3(2H)-pyridazinone

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About This Item

Empirical Formula (Hill Notation):
C19H18N4O2
CAS Number:
74150-27-9
Molecular Weight:
334.37
MDL number:
MFCD00761648
UNSPSC Code:
41116107
PubChem Substance ID:
329830936
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

pimobendan

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C(C1=CC=C(NC(C2=CC=C(OC)C=C2)=N3)C3=C1)=NN4)CC4=O

InChI

1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)

InChI key

GLBJJMFZWDBELO-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pimobendan for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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[Calcium mobilizers and calcium sensitizers].
Masashi Arai
Nihon rinsho. Japanese journal of clinical medicine, 69 Suppl 9, 417-422 (2012-06-26)
M W S Martin et al.
The Journal of small animal practice, 51(8), 428-436 (2010-07-31)
To review the association between clinical signs and diagnostic findings and the survival time of dogs with dilated cardiomyopathy (DCM), and any influence of treatment prescribed. A retrospective observational study of 367 dogs with DCM. Survival times until death or
Evaluation of pimobendan in dogs with cardiomegaly caused by preclinical mitral valve disease.
Adrian Boswood et al.
The Veterinary record, 168(8), 222-222 (2011-04-16)
Domenico Caivano et al.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 14(3), 431-444 (2012-08-14)
Interventional cardiac procedures are traditionally performed using fluoroscopy, or, more recently, transesophageal echocardiography (TEE). Neither modality is widely available to practicing cardiologists worldwide. We examined whether balloon valvuloplasty of pulmonic stenosis (PS) and transarterial occlusion of patent ductus arteriosus (PDA)
Andrea C Lantis et al.
American journal of veterinary research, 72(12), 1646-1651 (2011-12-01)
To evaluate the effect of administration of the labeled dosage of pimobendan to dogs with furosemide-induced activation of the renin-angiotensin-aldosterone system (RAAS). 12 healthy hound-type dogs. Dogs were allocated into 2 groups (6 dogs/group). One group received furosemide (2 mg/kg
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