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BCR140

Benzo[c]chrysene

BCR®, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C22H14
CAS Number:
194-69-4
Molecular Weight:
278.35
Beilstein:
1876196
MDL number:
MFCD00667762
UNSPSC Code:
41116107
PubChem Substance ID:
329774229
NACRES:
NA.24

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

c1ccc2c(c1)ccc3c2ccc4ccc5ccccc5c34

InChI

1S/C22H14/c1-3-7-18-15(5-1)11-14-21-20(18)13-12-17-10-9-16-6-2-4-8-19(16)22(17)21/h1-14H

InChI key

YZWGEMSQAMDWEM-UHFFFAOYSA-N

Analysis Note

For more information please see:
BCR140

Legal Information

BCR is a registered trademark of European Commission

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Shantu Amin et al.
Chemical research in toxicology, 16(2), 227-231 (2003-02-18)
Benzo[c]chrysene (BcC), an environmental pollutant, is a unique polycyclic aromatic hydrocarbon that possesses both a bay region and a fjord region in the same molecule. We previously demonstrated that both bay region and fjord region terminal rings are involved in
A Pal et al.
FEBS letters, 486(2), 163-166 (2000-12-13)
Carcinogenic activity of many polycyclic aromatic hydrocarbons (PAHs) is mainly attributed to their respective diol epoxides, which can be classified as either bay or fjord region depending upon the location of the epoxide function. The Pi class human glutathione (GSH)
A Luch et al.
Carcinogenesis, 19(4), 639-648 (1998-05-26)
Metabolic activation of the racemic benzo[c]chrysene-trans-9,10-, benzo[g]chrysene-trans-11,12- and dibenzo[a,l]pyrene-trans-11,12-dihydrodiols to fjord region syn- and anti-dihydrodiol epoxides by microsomes of Aroclor 1254-treated Sprague-Dawley rats has been examined. Since the fjord region dihydrodiol epoxides were hydrolytically unstable under the experimental conditions, their
A S Giles et al.
Chemical research in toxicology, 10(11), 1275-1284 (1997-12-24)
The metabolic activation in mouse skin of benzo[c]chrysene (B[c]C), a weakly carcinogenic polycyclic aromatic hydrocarbon (PAH) present in coal tar and crude oil, was investigated. Male Parkes mice were treated topically with 0.5 mumol of B[c]C, and DNA was isolated
Federica Nalin et al.
Analytical and bioanalytical chemistry, 410(3), 1123-1137 (2017-11-10)
Retention indices (I) for 45 polycyclic aromatic hydrocarbons (PAHs) and 63 methyl-substituted PAHs were determined by gas chromatography - mass spectrometry (GC-MS) using two different stationary phases: a Rxi-PAH phase (a "higher phenyl-content stationary phase") and a 50% (mole fraction)

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