Skip to Content
Merck
All Photos(1)

Key Documents

493732

Sigma-Aldrich

1,4-Butanediol

ReagentPlus®, 99%

Synonym(s):

1,4-Butylene glycol, Tetramethylene glycol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
HO(CH2)4OH
CAS Number:
Molecular Weight:
90.12
Beilstein:
1633445
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor density

3.1 (vs air)

Quality Level

product line

ReagentPlus®

Assay

99%

form

solid or viscous liquid

autoignition temp.

698 °F

refractive index

n20/D 1.445 (lit.)

bp

230 °C (lit.)

mp

16 °C (lit.)

density

1.017 g/mL at 25 °C (lit.)

functional group

hydroxyl

SMILES string

OCCCCO

InChI

1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2

InChI key

WERYXYBDKMZEQL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

1,4-Butanediol can be used as a reactant to prepare:
  • Homoallyl alcohol (3-buten-1-ol) and tetrahydrofuran via vapor-phase dehydration using ZrO2 as a catalyst.
  • Poly(1,4-butanediol succinate) polymer by reacting with succinic anhydride.
  • Biodegradable homopolyesters [poly(butylene succinate) and poly(butylene adipate)] and copolyesters [poly(butylene succinate-co-butylene adipate)] by treating with succinic acid and adipic acid via esterification and deglycolization reaction.
  • Poly(1,4-butyl sebacate) by polyesterification reaction with sebacic acid or its derivatives.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

273.2 °F - closed cup

Flash Point(C)

134 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jennifer N Miller et al.
Chemical science, 11(20), 5191-5204 (2021-06-15)
In condensed phase chemistry, the solvent can have a significant impact on everything from yield to product distribution to mechanism. With regard to photo-induced processes, solvent effects have been well-documented for charge-transfer states wherein the redistribution of charge subsequent to
Cristina Martin et al.
Biochemical engineering journal, 53(2), 216-222 (2011-01-25)
A novel miniaturized system has been developed for measuring protein-protein interactions in solution with high efficiency and speed, and minimal use of protein. A chromatographic monolith synthesized in a capillary is used in the method to make interaction measurements by
Daehun Park et al.
Nature communications, 12(1), 263-263 (2021-01-13)
Clusters of tightly packed synaptic vesicles (SVs) are a defining feature of nerve terminals. While SVs are mobile within the clusters, the clusters have no boundaries consistent with a liquid phase. We previously found that purified synapsin, a peripheral SV
Anders Hamberg et al.
Chemical communications (Cambridge, England), 48(80), 10013-10015 (2012-09-05)
The enzyme Candida antarctica lipase B was subjected to site directed mutagenesis suggested by molecular modelling. The selectivity for the enzyme increased towards a range of diols over their corresponding monoesters as an effect of the mutations.
Sreejith J Nair et al.
Nature structural & molecular biology, 26(3), 193-203 (2019-03-06)
A crucial feature of differentiated cells is the rapid activation of enhancer-driven transcriptional programs in response to signals. The potential contributions of physicochemical properties of enhancer assembly in signaling events remain poorly understood. Here we report that in human breast

Protocols

99%; Glycerol, ≥99.5%; Tetraethylene glycol, 99%

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service