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33395

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Methamidophos

PESTANAL®, analytical standard

Synonym(s):

O,S-Dimethyl phosphoramidothioate

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About This Item

Empirical Formula (Hill Notation):
C2H8NO2PS
CAS Number:
Molecular Weight:
141.13
Beilstein:
8137714
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
NMR: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water (Karl Fischer)

mp

42-45 °C

suitability

passes test for identity (NMR)

application(s)

agriculture
environmental

format

neat

storage temp.

−20°C

SMILES string

COP(N)(=O)SC

InChI

1S/C2H8NO2PS/c1-5-6(3,4)7-2/h1-2H3,(H2,3,4)

InChI key

NNKVPIKMPCQWCG-UHFFFAOYSA-N

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General description

Methamidophos is a broad spectrum organophosphate pesticide used for controlling a variety of plant and soil pests in agricultural crops.

Application

Methamidophos may be used as a reference standard for the determination of the analyte in human serum samples using gas chromatography with mass spectrometry (GC-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

413.6 °F - closed cup

Flash Point(C)

212 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Impacts of methamidophos on the biochemical, catabolic, and genetic characteristics of soil microbial communities.
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Critical reviews in environmental science and technology, 40(3), 778-788 (2008)
Simultaneous analysis of acephate and methamidophos in human serum by improved extraction and GC-MS.
Adachi N, et al.
Forensic Toxicology, 26(2), 76-76 (2008)
Gabriella Xavier Maretto et al.
Ecotoxicology and environmental safety, 80, 203-207 (2012-04-03)
Poisoning by organophosphorus insecticides is often accompanied by cardiac complications which may be serious and even fatal. However, the effects of these compounds on the cardiovascular mechanisms involved in blood pressure regulation are not known. The aim of this study
Guilherme L Emerick et al.
Toxicology, 292(2-3), 145-150 (2011-12-27)
The current Organisation for Economic Co-operation and Development (OECD) guidelines for evaluating organophosphorus-induced delayed neuropathy (OPIDN) require the observation of dosed animals over several days and the sacrifice of 48 hens. Adhering to these protocols in tests with enantiomers is
Teresa Rodríguez et al.
Occupational and environmental medicine, 69(2), 119-125 (2011-07-05)
This study assessed pesticide exposure of children in rural Nicaragua in relation to parental pesticide use, from around conception to current school age, as part of an epidemiological evaluation of neurodevelopment effects. We included 132 children whose parents were subsistence

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