03117057001
Roche
Bovine Serum Albumin Fraction V, heat shock, fatty acid free
from bovine serum
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About This Item
UNSPSC Code:
12352106
Recommended Products
biological source
bovine
Quality Level
Assay
≥98%
form
lyophilized
packaging
pkg of 100 g
manufacturer/tradename
Roche
pH
~7.0
shipped in
wet ice
storage temp.
2-8°C
General description
BSA is a single polypeptide chain consisting of about 583 amino acid residues and no carbohydrates. At pH 5-7, it contains 17 intra-chain disulfide bridges and one sulfhydryl group.
Application
- Pharmacological assays; ion-binding, transport, or immunological studies
- Fatty acid and lipid research
- Stabilization of proteins and enzymes against proteolysis and denaturation
Biochem/physiol Actions
The fatty acids that are insoluble in circulating plasma are transported primarily by serum. The human serum albumin and bovine serum albumin share 76% sequence homology. Being the most abundant protein in the circulatory system, it participates in the maintenance of blood pH and carries several endogenous and exogenous compounds, including fatty acids, metal, amino acids, steroids and drugs.
Quality
Purity: ≥98% albumin (electrophoresis), ≥98% protein
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)
Specifications
Moisture: ≤5%
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Putnam F, et al.
The Plasma Proteins: Structure, Function, and Genetic Control, 5 (2012)
Emilio P Mottillo et al.
Methods in enzymology, 538, 263-278 (2014-02-18)
Intracellular lipolysis is an important cellular process in key metabolic tissues, and while much is known about the enzymatic basis of lipolysis, our understanding of how these processes are organized and regulated within cells is incomplete. Lipolysis takes place on
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Journal of the American Society for Mass Spectrometry, 15(8), 1237-1247 (2004-07-28)
Serum albumin is the principal transporter of fatty acids that are otherwise insoluble in circulating plasma. While the crystal structure of human serum albumin (HSA) as well as its binding with fatty acids has been characterized, the three dimensional structure
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