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Key Documents

ABC323

Sigma-Aldrich

Anti-HMMR Antibody/CD168

from rabbit, purified by affinity chromatography

Synonym(s):

Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

primate (based on 100% sequence homology), monkey (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)

technique(s)

western blot: suitable

NCBI accession no.

NP_001136028

UniProt accession no.

O75330

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... HMMR(3161)

General description

Hyaluronan mediated motility receptor (HMMR) is also called Receptor for hyaluronan-mediated motility (RHAMM), Intracellular hyaluronic acid-binding protein (IHABP), and CD_antigen 168 (CD168). HMMR is involved in cell motility, and is also linked to cellular transformation and metastasis formation, regulation of extracellular-regulated kinase (ERK) activity. HMMR is expressed in breast cancer cell lines and in normal breast tissue.

Immunogen

KLH-conjugated linear peptide corresponding to the of human HMMR.

Application

Anti-HMMR Antibody/CD168 detects level of HMMR/CD168 & has been published & validated for use in HMMR/CD168.

Quality

Evaluated by Western Blotting in MDA-MB-435 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected HMMR in 10 µg of MDA-MB-435 cell lysate.

Target description

~85 kDa observed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Luke J Fulcher et al.
EMBO reports, 20(9), e47495-e47495 (2019-07-25)
The concerted action of many protein kinases helps orchestrate the error-free progression through mitosis of mammalian cells. The roles and regulation of some prominent mitotic kinases, such as cyclin-dependent kinases, are well established. However, these and other known mitotic kinases
Luke J Fulcher et al.
Science signaling, 11(531) (2018-05-24)
Members of the casein kinase 1 (CK1) family of serine-threonine protein kinases are implicated in the regulation of many cellular processes, including the cell cycle, circadian rhythms, and Wnt and Hedgehog signaling. Because these kinases exhibit constitutive activity in biochemical

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