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475915

Sigma-Aldrich

Anti-Myeloperoxidase Rabbit pAb

liquid, Calbiochem®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MPO(4353)

General description

Rabbit polyclonal antibody purified by ammonium sulfate precipitation followed by DEAE-Sephacel ion exchange chromatography. Recognizes the myeloperoxidase protein.
Recognizes myeloperoxidase in human neutrophil granules.
This Anti-Myeloperoxidase Rabbit pAb is validated for use in ELISA, Immunoelectrophoresis for the detection of Myeloperoxidase.

Immunogen

Human
purified, human neutrophil myeloperoxidase

Application

ELISA (≥ 1:4000)

Immunoelectrophoresis (see comments)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Generates a single arc by immunoelectrophoresis against human neutrophil granule extract and purified MPO. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kashish Manchanda et al.
Arteriosclerosis, thrombosis, and vascular biology, 38(8), 1859-1867 (2018-06-16)
Objective- The leukocyte heme-enzyme MPO (myeloperoxidase) exerts proinflammatory effects on the vascular system primarily linked to its catalytic properties. Recent studies have shown that MPO, depending on its cationic charge, mediates neutrophil recruitment and activation. Here, we further investigated MPO's

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