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1.10317

Millipore

Fractogel® EMD BioSEC (S)

Synonym(s):

Fractogel® EMD BioSEC (S)

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About This Item

UNSPSC Code:
41115711

ligand

(Modified pore structure)

Quality Level

400

description

for size exclusion chromatography (SEC), suspension in 20% ethanol and 150 mM NaCl (20-40 µm)

product line

Fractogel®

parameter

100 cm/hr max. flow rate
8 bar pressure

matrix active group

Methacrylate

mean particle size

20-40 μm

transition temp

flash point 35 °C (calculated)

density

1.43 g/cm3 at 20 °C

application(s)

viral therapy

separation technique

size exclusion (SEC)

storage temp.

2-30°C

General description

Size exclusion chromatography for separation of proteins in the range between 5 kDa and 1000 kDa

Features and Benefits

Fractogel® EMD BioSEC (S) enables users to:

  • Effectively remove dimer and high molecular weight aggregates and complete an efficient polishing of blood plasma factors
  • Determine apparent molecular weights of proteins
  • Move predictably and efficiently from bench scale to manufacturing scale processing
  • Create a robust, consistent, and transferable process

Packaging

Plastic bottle

Analysis Note

Appearance: Milky turbid suspension,free from impurities(foreign particles)
Microscopic evaluation: Uniform sphericalparticles, noagglomerates, nofines
Extractable matter (water): ≤ 0.03 %
Cerium: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 5.0 bar
Particle size (d10): 20 - 28 µm
Particle size (d50): 24 - 34 µm
Particle size (d90): 28 - 38 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Function test (b:a): ≤ 0.7
function test (c:d): ≤ 0.05
Functional Test: Separation of bovine serum albumin, ovalbumin and cytochrom C

Legal Information

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Flame
GHS02

Signal Word

Warning

Hazard Statements

H226

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

95.0 °F

Flash Point(C)

35 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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