939692

Poly(glycerol sebacate) methacrylate

degree of methacrylation 20%, contains 150 ppm MEHQ as inhibitor

• Synonym(s): PGS-MA
• Linear Formula: [CH₂CH(O₂C₄H₅)CH₂OOC(CH₂)₈COO]_n
• UNSPSC Code: 12352201

Properties

• Quality Level: 100
• form: (liquid/paste)
• contains: 150 ppm MEHQ as inhibitor
• color: white/yellow
• storage temp.: −20°C

Description

General description

Poly(glycerol sebacate) methacrylate (PGS-MA) is a photopolymerizable biodegradable elastomer with tunable mechanical properites that can be used for bioprinting, tissue engineering, and regenerative medicine applications including cardiac, nerve, and muscle tissues. PGS is derived from the naturally occuring metabolites glycerol and sebacic acid, which have both been used for FDA approved biomedical applications. The polymer backbone contains ester bonds that can undergo hydrolytic degradation and can also be covalently crosslinked to form a 3D network at higher temperatures under vacuum. The addition of the methacrylate functional groups provides another mechanism of crosslinking via photopolymerization. The PGS-MA can be quickly and efficiently crosslinked under the exposure of UV and visible light in the presence of a photoinitiatior.

Application

• Soft tissue engineering such as blood vessels, cornea and nerve tissue
• Orthopedic implants and regenerative medicine application like muscle tissues
• Nanoparticle formulation and drug delivery systems
• Flexible wearable or implantable bioelectronic applications

Features and Benefits

• Flexible elastomer with tunable mechanical properties
• Higher reversible deformation properties
• Shape memory
• Bioresorbable polymer

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable