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712523

Sigma-Aldrich

O-(3-Carboxypropyl)-O′-[2-(3-mercaptopropionylamino)ethyl]-polyethylene glycol

Mw 5000

Synonym(s):

Polyethylene glycol, α-Mercapto-ω-carboxy-PEG

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About This Item

CAS Number:
UNSPSC Code:
51171641
NACRES:
NA.22

form

lumps

mol wt

Mw 5000

reaction suitability

reagent type: cross-linking reagent

Ω-end

thiol

α-end

carboxylic acid

storage temp.

−20°C

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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Articles

Sigma-Aldrich.com presents an article regarding Polyethylene Glycol Building Blocks for PEGylation.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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