236314

p-Toluidine

99.6%

• Synonym(s): 4-Aminotoluene, 4-Methylaniline
• Linear Formula: CH₃C₆H₄NH₂
• CAS Number: 106-49-0
• Molecular Weight: 107.15
• Beilstein: 471281
• EC Number: 203-403-1
• MDL number: MFCD00007906
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854162
• NACRES: NA.22

Properties

• vapor density: 3.9 (vs air)
• vapor pressure: 0.26 mmHg ( 25 °C); 0.66 mmHg ( 38 °C)
• Assay: 99.6%
• form: crystalline
• autoignition temp.: 899 °F
• expl. lim.: 6.6 %
• pH: 7.8 (7 g/L)
• bp: 200 °C (lit.)
• mp: 41-46 °C (lit.)
• solubility: water: soluble 135 part(lit.); acetone: freely soluble(lit.); alcohol: freely soluble(lit.); carbon disulfide: freely soluble(lit.); diethyl ether: freely soluble(lit.); methanol: freely soluble(lit.); oil: freely soluble(lit.)
• density: 0.973 g/mL at 25 °C (lit.)
• SMILES string: Cc1ccc(N)cc1
• InChI: 1S/C7H9N/c1-6-2-4-7(8)5-3-6/h2-5H,8H2,1H3
• InChI key: RZXMPPFPUUCRFN-UHFFFAOYSA-N

Description

General description

p-Toluidine undergoes oxidative coupling reaction with catecholamine to form an orange water-soluble dye during flow injection-spectrophotometric determination of catecholamine drugs.

Application

p-Toluidine has been used in preparation of:

• aromatic azo compounds
• bidentate Schiff base ligands via condensation with salicylaldehyde

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331,H317,H319,H351,H410
• Precautionary Statements: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Skin Sens. 1A
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves