Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

236314

Sigma-Aldrich

p-Toluidine

99.6%

Synonym(s):

4-Aminotoluene, 4-Methylaniline

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3C6H4NH2
CAS Number:
106-49-0
Molecular Weight:
107.15
Beilstein:
471281
EC Number:
203-403-1
MDL number:
MFCD00007906
UNSPSC Code:
12352100
PubChem Substance ID:
24854162
NACRES:
NA.22

vapor density

3.9 (vs air)

vapor pressure

0.26 mmHg ( 25 °C)
0.66 mmHg ( 38 °C)

Assay

99.6%

form

crystalline

autoignition temp.

899 °F

expl. lim.

6.6 %

pH

7.8 (7 g/L)

bp

200 °C (lit.)

mp

41-46 °C (lit.)

solubility

water: soluble 135 part(lit.)
acetone: freely soluble(lit.)
alcohol: freely soluble(lit.)
carbon disulfide: freely soluble(lit.)
diethyl ether: freely soluble(lit.)
methanol: freely soluble(lit.)
oil: freely soluble(lit.)

density

0.973 g/mL at 25 °C (lit.)

SMILES string

Cc1ccc(N)cc1

InChI

1S/C7H9N/c1-6-2-4-7(8)5-3-6/h2-5H,8H2,1H3

InChI key

RZXMPPFPUUCRFN-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

p-Toluidine undergoes oxidative coupling reaction with catecholamine to form an orange water-soluble dye during flow injection-spectrophotometric determination of catecholamine drugs.

Application

p-Toluidine has been used in preparation of:
  • aromatic azo compounds
  • bidentate Schiff base ligands via condensation with salicylaldehyde

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Skin Sens. 1A

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCH4698
BCCF3281
BCCD5094
BCCC3266
BCCB6356

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Flow injection-spectrophotometeric determination of some catecholamine drugs in pharmaceutical preparations via oxidative coupling reaction with< i> p</i>-toluidine and sodium periodate.
Abdulrahman LK, et al.
Analytica Chimica Acta, 538(1), 331-335 (2005)
Ruthenium (II) complexes containing bidentate Schiff bases and their antifungal activity.
Dharmaraj N, et al.
Transition Met. Chem. (London), 26(1-2), 105-109 (2001)
Paul G Stevenson et al.
Journal of chromatography. A, 1218(45), 8255-8263 (2011-10-11)
Several simple techniques are presented for the identification of the boundaries of chromatographic peaks. These methods provide a significant reduction in the time needed to perform the rapid, automatic calculation of the central peak moments and to evaluate the quality
Shunji Ito et al.
The Journal of organic chemistry, 70(6), 2285-2293 (2005-03-12)
[reaction: see text] N,N-Di(6-azulenyl)-p-toluidine (1a) and N,N,N',N'-tetra(6-azulenyl)-p-phenylenediamine (2a) and their derivatives with 1,3-bis(ethoxycarbonyl) substituents on each 6-azulenyl group (1b and 2b) were prepared by Pd-catalyzed amine azulenylation and characterized as a study into new aromatic amines for multistage amphoteric redox
Abdessamad Grirrane et al.
Nature protocols, 5(3), 429-438 (2010-03-06)
This protocol describes the aerobic oxidation of aromatic anilines to aromatic azo compounds using gold (Au) nanoparticles supported on TiO(2) as a catalyst. Yields above 98% are achieved under a few bars of oxygen pressure. It should be noted that
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service