191884

Hydroxypropyl cellulose

average M_w ~100,000, powder, 20 mesh particle size (99% through)

• CAS Number: 9004-64-2
• MDL number: MFCD00132688
• UNSPSC Code: 12162002
• NACRES: NA.23

Properties

• description: biological oxygen demand (BOD) 14,000 ppm
• form: powder
• autoignition temp.: 752 °F
• mol wt: average M_w ~100,000
• impurities: <5 wt. %
• particle size: 20 mesh (99% through)
• pH: 5.0-8.5
• interfacial tension mineral oil: 12.5 dyn/cm, 0.1 wt. % in H₂O (vs. mineral oil)
• viscosity: 65-175 cP, 5 wt. % in H₂O(25 °C, Brookfield, spindle #1) (30 rpm)(lit.)
• solubility: polar organic solvents: soluble
• density: 0.5 g/mL at 25 °C (lit.)
• InChI: 1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3
• InChI key: RRHXDYJWVYFMKV-UHFFFAOYSA-N

Description

General description

Hydroxypropyl cellulose (HPC) is a neutral polysaccharide prepared by reacting propylene oxide with alkali cellulose at high temperatures and pressure. It is soluble in water and many polar organic solvents. HPC is widely used as a food additive and in drug delivery systems.

Application

Hydroxypropyl cellulose can be used in the following applications:

• HPC is soluble in organic solvents which makes it suitable for the preparation of polymer gel electrolytes for electrochemical devices. The network-forming ability of HPC can improve the mechanical and electrical properties of gel electrolytes.
• Electrospun hydroxypropyl cellulose nanofibres can be used to develop drug delivery systems for a variety of hydrophobic drugs.
• Hydroxypropylcellulose combined with an effervescent agent like sodium carbonate can be usedas a binder and functional material to prepare floating tablets for thecontrolled release of ofloxacin.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves