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T3394

Sigma-Aldrich

Tetraethylene glycol monooctyl ether

liquid, ≥98% (GC)

Synonym(s):

C8E4, Octyl tetraethylene glycol ether, Octyltetraglycol

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About This Item

Linear Formula:
CH3(CH2)7(OCH2CH2)4OH
CAS Number:
19327-39-0
Molecular Weight:
306.44
Beilstein:
1781226
MDL number:
MFCD00043033
UNSPSC Code:
12161900
PubChem Substance ID:
24900138

description

non-ionic

Quality Level

200

Assay

≥98% (GC)

form

liquid

mol wt

306.44 g/mol

density

0.969 g/mL at 20 °C (lit.)

SMILES string

CCCCCCCCOCCOCCOCCOCCO

InChI

1S/C16H34O5/c1-2-3-4-5-6-7-9-18-11-13-20-15-16-21-14-12-19-10-8-17/h17H,2-16H2,1H3

InChI key

FEOZZFHAVXYAMB-UHFFFAOYSA-N

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General description

Tetraethylene glycol monooctyl ether is a surfactant.

Application

Reported to be useful in solubilizing membrane proteins.
Tetraethylene glycol monooctyl ether has been used in a study to assess thermal diffusion behavior of nonionic surfactants in water. It has also been used in a study to investigate unusual micelle and surface adsorption behavior in mixtures of surfactants.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Hui Ning et al.
The journal of physical chemistry. B, 110(22), 10746-10756 (2006-06-15)
We studied the thermal diffusion behavior of hexaethylene glycol monododecyl ether (C12E6) in water by means of thermal diffusion forced Rayleigh scattering (TDFRS) and determined Soret coefficients, thermal diffusion coefficients, and diffusion constants at different temperatures and concentrations. At low
Javier Abellón-Ruiz et al.
Nature microbiology, 2(12), 1616-1623 (2017-10-19)
The Gram-negative bacterial outer membrane (OM) is a unique bilayer that forms an efficient permeation barrier to protect the cell from noxious compounds
Raquel Rodríguez-Alonso et al.
Nature chemical biology, 16(9), 1019-1025 (2020-06-24)
The β-barrel assembly machinery (BAM) inserts outer membrane β-barrel proteins (OMPs) in the outer membrane of Gram-negative bacteria. In Enterobacteriacea, BAM also mediates export of the stress sensor lipoprotein RcsF to the cell surface by assembling RcsF-OMP complexes. Here, we
J B Vieira et al.
Langmuir : the ACS journal of surfaces and colloids, 21(10), 4441-4451 (2005-07-22)
Micellization and adsorption at the air-solution interface of binary mixtures of the triblock copolymer of ethylene oxide and propylene oxide, EO23PO52EO23 (EPE), and the surfactants sodium dodecyl sulfate (SDS), dodecyl trimethylammonium chloride (DTAC), and tetraethylene glycol monooctyl ether (C8EO4) have
Thomas Noe Perry et al.
Biochimica et biophysica acta. Biomembranes, 1861(2), 466-477 (2018-11-18)
Membrane protein (MP) complexes play key roles in all living cells. Their structural characterisation is hampered by difficulties in purifying and crystallising them. Recent progress in electron microscopy (EM) have revolutionised the field, not only by providing higher-resolution structures for
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