SML0581

SR 58894A

≥98% (HPLC)

• Synonym(s): 3-(2-Allylphenoxy)-1-[(1S)-1,2,3,4-tetrahydro-naphth-1-ylamino]-(2 S)-2-propanol hydrochloride, SR58894A
• Empirical Formula (Hill Notation): C₂₂H₂₇NO₂ · HCl
• CAS Number: 132017-03-9
• Molecular Weight: 373.92
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -19 to -25°, c = 1 in methanol
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C

Description

Biochem/physiol Actions

SR58894A is a potent and selective antagonist of β3-adrenergic receptor.

SR 58894A is also known as (3-(2-allylphenoxy)-1-[(1 S)-1,2,3,4-tetrahydronaphth-1-ylamino]-(2 S)-2-propanol hydrochloride, Kissei). It has the ability to antagonize relaxation, stimulated by isoprenaline.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS09
• Signal Word: Warning
• Hazard Statements: H410
• Precautionary Statements: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable