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Key Documents

SAB4501902

Sigma-Aldrich

Anti-MMP14 (Cleaved-Tyr112) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

MATRIX METALLOPROTEINASE 14, MEMBRANE-TYPE, MEMBRANE-TYPE MATRIX METALLOPROTEINASE 1, MT1-MMP, matrix metalloproteinase 14 (membrane-inserted)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 53 kDa

species reactivity

rat, human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
western blot: 1:500-1:1000

UniProt accession no.

P50281

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

proteolytically cleaved (Tyr112)

Gene Information

human ... MMP14(4323)

General description

Anti-MMP14 (Cleaved-Tyr112) Antibody detects endogenous levels of fragment of activated MMP14 (Cleaved-Tyr112) protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP14.

Immunogen Range: 93-142

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dominique Trudel et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 27(10), 1394-1404 (2014-03-08)
The purpose of this study was to evaluate whether the membrane type 1 matrix metalloproteinase-14 (or MT1-MMP) tissue expression, as assessed visually on digital slides and by digital image analysis, could predict outcomes in women with ovarian carcinoma. Tissue microarrays
Huayi Wang et al.
Cell biochemistry and biophysics, 70(2), 729-734 (2014-05-03)
The objective of the study was to evaluate the expression of matrix metalloproteinase-14 (MMP-14) in cervical carcinoma and correlate its expression with clinicopathological parameters, recurrence, and survival of the patients. The expressions of MMP-14 in normal cervical mucosa and cervical

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