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P5234

Sigma-Aldrich

Purvalanol B

≥97% (HPLC), solid

Synonym(s):

(2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol, NG 95

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About This Item

Empirical Formula (Hill Notation):
C20H25ClN6O3
CAS Number:
212844-54-7
Molecular Weight:
432.90
MDL number:
MFCD04118312
UNSPSC Code:
12352200
PubChem Substance ID:
329820218
NACRES:
NA.77

Quality Level

100

Assay

≥97% (HPLC)

form

solid

solubility

DMSO: soluble 37 mg/mL
H2O: insoluble

shipped in

dry ice

storage temp.

−20°C

SMILES string

CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(O)=O)c(Cl)c2)c3ncn(C(C)C)c3n1

InChI

1S/C20H25ClN6O3/c1-10(2)15(8-28)24-20-25-17(16-18(26-20)27(9-22-16)11(3)4)23-12-5-6-13(19(29)30)14(21)7-12/h5-7,9-11,15,28H,8H2,1-4H3,(H,29,30)(H2,23,24,25,26)/t15-/m0/s1

InChI key

ZKDXRFMOHZVXSG-HNNXBMFYSA-N

Biochem/physiol Actions

Purvalanol B is a cyclin-dependent; 2,6,9-substituted kinase inhibitor.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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