O1376
Orotidine 5′-monophosphate trisodium salt
≥99% (HPLC), powder
Synonym(s):
OMP, Orotidylic acid
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About This Item
Linear Formula:
C10H10N2O11PNa3
CAS Number:
Molecular Weight:
434.14
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Recommended Products
Quality Level
Assay
≥99% (HPLC)
form
powder
color
white
storage temp.
−20°C
SMILES string
[Na].OC1C(O)C(OC1COP(O)(O)=O)N2C(=O)NC(=O)C=C2C(O)=O
InChI
1S/C10H13N2O11P.Na.H/c13-5-1-3(9(16)17)12(10(18)11-5)8-7(15)6(14)4(23-8)2-22-24(19,20)21;;/h1,4,6-8,14-15H,2H2,(H,16,17)(H,11,13,18)(H2,19,20,21);;
InChI key
PSBNOTIIJINWKE-UHFFFAOYSA-N
Related Categories
Application
Orotidine 5′-monophosphate (OMP) is the direct precursor of uridine 5′-monophosphate (UMP) in pyrimidine biosynthesis. OMP is used to study the specificity, kinetics, structures and mechanisms of orotidine 5′-monophosphate decarboxylase(s) (EC 4.1.1.23).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Yang Chen et al.
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M E Meza-Avina et al.
Mini reviews in medicinal chemistry, 8(3), 239-247 (2008-03-14)
Orotidine 5'-monophosphate decarboxylase (ODCase) is among the most proficient enzymes, and catalyzes the decarboxylation of OMP to UMP. An overview of ODCase and various proposals for its catalytic mechanism of decarboxylation are briefly presented here. A number of inhibitors of
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