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NP9

Sigma-Aldrich

TERGITOL™

Type NP-9

Synonym(s):

Mono(p-nonylphenyl)ether, Nonoxynol-9, Polyethylene glycol mono(branched p-nonylphenyl) ether

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About This Item

CAS Number:
127087-87-0
MDL number:
MFCD00132411
UNSPSC Code:
12161900
NACRES:
NA.25

biological source

(chemical)

description

non-ionic

type

Type NP-9

form

liquid

mol wt

616 g/mol

CMC

60 ppm

transition temp

cloud point 54 °C

solubility

water: soluble

HLB

12.9

SMILES string

CCCCCCCCCC1=CC=C(C=C1)OCCO

InChI

1S/C17H28O2/c1-2-3-4-5-6-7-8-9-16-10-12-17(13-11-16)19-15-14-18/h10-13,18H,2-9,14-15H2,1H3

InChI key

KUXGUCNZFCVULO-UHFFFAOYSA-N

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General description

Tergitol NP 9 is a versatile nonionic surfactant that finds applications in cell biology, biochemical, and formulation research. Its unique properties, arising from its hydrophilic and hydrophobic components, make it an effective wetting agent, emulsifier, dispersant, and detergent.

In protein research, Tergitol plays a crucial role in facilitating protein analysis and purification. Its detergent properties enable it to lyse cells, releasing soluble proteins, and solubilizing membrane proteins and lipids, making them accessible for further study. Additionally, it may also be employed in protein crystallization, preventing non-specific binding during affinity purification and immunoassay procedures, and serves as an additive in electrophoresis. Tergitol, extending beyond protein research, finds versatile applications in various industries, serving as a valuable component in formulation research due to its ability to emulsify, disperse, and solubilize, thereby enhancing the stability and homogeneity of different mixtures.

Surfactants, possessing both hydrophilic and hydrophobic components, fall into two main categories: ionic, which ionize in water (anionic, cationic, or ampholytic), and nonionic, which do not ionize. Tergitol NP 9 product is a nonionic surfactant with diverse applications such as emulsification, dispersion, solubilization, and detergent use.

Application

TERGITOL™ has been used in cytotoxicity assays to treat Vero cells for producing cytotoxic (100% dead) controls. It may be used in paper & textile processing, laundry, dust control, agrochemicals, metalworking fluids and paints & coatings.
Tergitol has been used in a study to assess a method to determine nickel using ultrasonic-assisted cloud point extraction. It has also been used in a study to investigate a method for the detection of Salmonella Enteritidis via an Enteritidis-specific real time PCR assay

Features and Benefits

  • Excellent detergent quality
  • Outstanding wetting
  • Flexible solubility characteristics
  • Unique handling properties
  • Low odor
  • Can be rinsed easily
  • Chemically stable in the presence of dilute acids, bases, and salts
  • Compatible with organic solvents, soaps, anionic, and other nonionic surfactants

Other Notes

Polyglycol ether (nonionic) surfactants.
For additional information on our range of Biochemicals, please complete this form.

Legal Information

TERGITOL is a trademark of The Dow Chemical Company ("Dow") or an affiliated company of Dow

comparable product

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Description
Pricing

NP10

TERGITOL™, Type NP-10

NP7

TERGITOL™, Type NP-7

Signal Word

Danger

Hazard Statements

H302 + H332,H318,H411

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

476.6 °F - closed cup

Flash Point(C)

247 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

EU REACH Annex XIV (Authorisation List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adriana Pliego Zamora et al.
Virology, 495, 18-32 (2016-05-07)
West Nile Virus (WNV) is a mosquito-borne flavivirus that can cause neuroinvasive disease in humans and animals for which no therapies are currently available. We studied an established combination of monoterpene alcohols (CMA) derived from Melaleuca alternifolia, against WNV infection.
Bwalya Lungu et al.
Journal of food protection, 75(4), 743-747 (2012-04-11)
Conventional culture methods have traditionally been considered the "gold standard" for the isolation and identification of foodborne bacterial pathogens. However, culture methods are labor-intensive and time-consuming. A Salmonella enterica serotype Enteritidis-specific real-time PCR assay that recently received interim approval by
Determination of estrogens in human urine by high-performance liquid chromatography/diode array detection with ultrasound-assisted cloud-point extraction
Y Zou, et al.
Analytical Biochemistry, 421, 7-7 (2012)
Maryam Seyedmajidi et al.
Biomedical materials (Bristol, England), 13(2), 025015-025015 (2017-11-15)
Bone defects are common and persistent problems in clinical orthopedics and dentistry. The development of synthetic reconstruction materials is essential owing to the restricted access to natural bone grafts, disease transmission risks, surgical costs, donor-site morbidity, infections, and immune response-related
Emily S Savela et al.
PLoS biology, 18(3), e3000651-e3000651 (2020-03-20)
Rapid antibiotic susceptibility testing (AST) for Neisseria gonorrhoeae (Ng) is critically needed to counter widespread antibiotic resistance. Detection of nucleic acids in genotypic AST can be rapid, but it has not been successful for β-lactams (the largest antibiotic class used
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