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E9904

Sigma-Aldrich

Ergtoxin Peptide

>98% (HPLC), lyophilized powder, recombinant, expressed in E. coli

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

Pricing and availability is not currently available.

Product Name

Ergtoxin from Centruroides noxius (Scorpion), recombinant, expressed in E. coli, >98% (HPLC), lyophilized powder

recombinant

expressed in E. coli

Quality Level

Assay

>98% (HPLC)

form

lyophilized powder

mol wt

apparent mol wt ~4.7 kDa by SDS-PAGE

solubility

aqueous buffer: soluble

storage temp.

−20°C

SMILES string

N%16%15[C@@](O[C@](C%16=O)(NC(=O)[C@H]%19CN([C@@H]%20Cc%21c%22c([nH]c%21)cccc%22C%20=C%19)C)C(C)C)([C@H]%17N(CCC%17)C(=O)[C@@H]%15Cc%18ccccc%18)O.N98[C@@](O[C@](C9=O)(NC(=O)[C@H]%11CN([C@@H]%12Cc%13c%14c([nH]c%13)cccc%14C%12=C%11)C)C(C)C)([C@H]%10N(CCC%10

InChI

1S/C35H39N5O5.C32H41N5O5.C31H39N5O5/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34;1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)

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This Item
I0779V3638P5739
recombinant

expressed in E. coli

recombinant

expressed in NSO cells

recombinant

expressed in NSO cells

recombinant

expressed in baculovirus infected Sf21 cells

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mol wt

apparent mol wt ~4.7 kDa by SDS-PAGE

mol wt

36 kDa by SDS-PAGE

mol wt

dimer 50 kDa by SDS-PAGE, monomer 25 kDa by SDS-PAGE

mol wt

~38 kDa by SDS-PAGE

Biochem/physiol Actions

A novel ERG1 (KV11.1) K+ channel blocker

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Miguel Corona et al.
FEBS letters, 532(1-2), 121-126 (2002-12-03)
Twenty-three novel sequences similar to Ergtoxin (ErgTx) were obtained by direct sequencing of peptides or deduced from gene cloned using cDNAs of venomous glands of Centruroides (C.) elegans, C. exilicauda, C. gracilis, C. limpidus limpidus, C. noxius and C. sculpturatus.

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