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A9111

Sigma-Aldrich

(±)-AMPA hydrobromide

≥98% (HPLC)

Synonym(s):

(±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C7H10N2O4 · HBr
CAS Number:
171259-81-7
Molecular Weight:
267.08
MDL number:
MFCD00055183
UNSPSC Code:
12352200
PubChem Substance ID:
329771033
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

off-white to light tan

solubility

H2O: ≥10 mg/mL

storage temp.

2-8°C

SMILES string

Br.Cc1onc(O)c1CC(N)C(O)=O

InChI

1S/C7H10N2O4.BrH/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H

InChI key

KUAHVIUZGLGASU-UHFFFAOYSA-N

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Biochem/physiol Actions

(±)-AMPA is a potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Kayoung Han et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(50), 10081-10095 (2019-11-02)
Neurovascular coupling (NVC), the interaction between neural activity and vascular response, ensures normal brain function by maintaining brain homeostasis. We previously reported altered cerebrovascular responses during functional hyperemia in chronically stressed animals. However, the underlying neuronal-level changes associated with those

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