A1076
BAPTA-AM
≥95% (HPLC), powder, intracellular Ca²⁺ store chelator
Synonym(s):
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester)
About This Item
Recommended Products
product name
BAPTA-AM, ≥95% (HPLC)
Quality Level
Assay
≥95% (HPLC)
form
powder
storage temp.
−20°C
SMILES string
CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccccc1OCCOc2ccccc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O
InChI
1S/C34H40N2O18/c1-23(37)47-19-51-31(41)15-35(16-32(42)52-20-48-24(2)38)27-9-5-7-11-29(27)45-13-14-46-30-12-8-6-10-28(30)36(17-33(43)53-21-49-25(3)39)18-34(44)54-22-50-26(4)40/h5-12H,13-22H2,1-4H3
InChI key
YJIYWYAMZFVECX-UHFFFAOYSA-N
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General description
Application
- to reduce the elevation of cleaved caspase-3
- to block cell death, inhibit ROS (reactive oxygen species) production and inhibit caspase-8 activation
- to exclude the effect of changes in intracellular Ca2+ ([Ca2+]i) concentration during seizure induction
- to eliminate the increase of [Ca2+]i induced by 6-hydroxydopamine (6-OHDA)
Biochem/physiol Actions
Linkage
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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