68957
Tris(2-carboxyethyl)phosphine hydrochloride
BioUltra, suitable for electrophoresis, SDS-PAGE tested
Synonym(s):
TCEP.HCL, TCEP
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About This Item
Empirical Formula (Hill Notation):
C9H15O6P · HCl
CAS Number:
Molecular Weight:
286.65
Beilstein:
3724376
MDL number:
UNSPSC Code:
12352128
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
product line
BioUltra
Assay
97.5-102.5%
form
powder
technique(s)
electrophoresis: suitable
solubility
H2O: soluble
suitability
SDS-PAGE tested
SMILES string
Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI
1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChI key
PBVAJRFEEOIAGW-UHFFFAOYSA-N
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General description
Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.
Application
TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.
Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.
Features and Benefits
The product has the following benefits:
- TCEP.HCL lowers reactive oxygen species levels.
- It increases glutathione levels and mitochondrial content.
- It has anti-cancer effects.
Analysis Note
agarose gel electrophorese corresponds to requirements
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 1
Certificates of Analysis (COA)
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