11009

L-Arginine

BioUltra, ≥99.5% (NT)

• Synonym(s): (S)-2-Amino-5-guanidinopentanoic acid
• Linear Formula: H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H
• CAS Number: 74-79-3
• Molecular Weight: 174.20
• Beilstein: 1725413
• EC Number: 200-811-1
• MDL number: MFCD00002635
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 329749274
• NACRES: NA.26

Properties

• product line: BioUltra
• Assay: ≥99.5% (NT)
• form: powder or crystals
• optical activity: [α]20/D +27.0±0.5°, c = 5% in 5 M HCl
• impurities: insoluble matter, passes filter test; ≤0.3% foreign amino acids
• ign. residue: ≤0.05% (as SO₄)
• loss: ≤0.1% loss on drying, 20 °C (HV)
• color: white
• pH: 10.5-12.0 (25 °C, 0.5 M in H₂O)
• mp: 222 °C (dec.) (lit.)
• solubility: H₂O: 0.5 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 0.5 M in H₂O
• UV absorption: λ: 260 nm A_max: ≤0.2; λ: 280 nm A_max: ≤0.1
• application(s): peptide synthesis
• SMILES string: N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
• InChI key: ODKSFYDXXFIFQN-BYPYZUCNSA-N
• Gene Information: human ... NOS1(4842) , NOS2(4843) ; rat ... Ppm1a(24666)

Description

Application

• L-Arginine-Dependent Nitric Oxide Production in the Blood of Patients with Type 2 Diabetes: A Pilot, Five-Year Prospective Study.: This study examines the role of L-Arginine in nitric oxide production in diabetic patients, proposing its potential benefits for managing vascular complications in diabetes (Stoian et al., 2024).

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Other Notes

Exhibits stabilizing effects on plant protoplasts; pH drift correction in IEF of proteins; Growth requirement of various microorganisms.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves