PHR1053
Albuterol sulfate
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Albuterol Sulfate
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About This Item
Empirical Formula (Hill Notation):
C26H44N2O10S
CAS Number:
Molecular Weight:
576.70
EC Number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to BP 302
traceable to Ph. Eur. S0150000
traceable to USP 1012633
API family
albuterol, salbutamol
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Gene Information
human ... ADRB2(154)
General description
Albuterol sulfate is a β2 adrenergic agonist and a bronchodilating agent, which is used in the treatment of asthma.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Albuterol sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by ultra-performance liquid chromatographic method with ultraviolet detection (UPLC-UV).
Albuterol sulfate may be used as a reference standard in determining the concentration of albuterol sulfate present in inhalers using reversed-phase high performance liquid chromatography (RP-HPLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA7128 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Repr. 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Comparison of conventional HPLC with UPLC method for determination of albuterol sulfate and it?s impurities in pharmaceutical formulation.
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Orient. J. Chem., 24(2), 537-544 (2008)
Determination of albuterol sulfate and its related substances in albuterol sulfate inhalation solution, 0.5% by RP-HPLC
Erram.VS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(4), 864-874 (2006)
Supercritical and near-critical carbon dioxide assisted low-temperature bubble drying
Sievers.ER, et al.
Industrial & Engineering Chemistry Research, 39(12), 4831-4836 (2000)
Clinical Practice. Mild asthma.
Elisabeth H Bel
The New England journal of medicine, 369(6), 549-557 (2013-08-09)
Huan Wang et al.
Biosensors & bioelectronics, 49, 14-19 (2013-05-28)
A multiplexed electrochemical biosensor has been developed for fast and sensitive detection of ractopamine (RAC), salbutamol (SAL) and clenbuterol (CLB) based on reduced graphene oxide (rGO) and silver-palladium alloy nanoparticles (AgPd NPs). In this paper, rGO with high conductivity was
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