82280

1,2-Propanediol

puriss. p.a., ACS reagent, ≥99.5% (GC)

• Synonym(s): 1,2-PDO, Propylene glycol
• Linear Formula: CH₃CH(OH)CH₂OH
• CAS Number: 57-55-6
• Molecular Weight: 76.09
• Beilstein: 1340498
• EC Number: 200-338-0
• MDL number: MFCD00064272
• UNSPSC Code: 12352100
• PubChem Substance ID: 57652909
• NACRES: NA.21

Properties

• grade: ACS reagent; puriss. p.a.
• Quality Level: 200
• vapor density: 2.62 (vs air)
• vapor pressure: 0.08 mmHg ( 20 °C)
• Assay: ≥99.5% (GC)
• form: viscous liquid
• autoignition temp.: 779 °F
• shelf life: 3 yr
• expl. lim.: 12.5 %
• impurities: ≤0.003% free acid (as CH₃COOH); ≤0.1% water
• evapn. residue: ≤0.005%
• ign. residue: <0.005% (as SO₄)
• refractive index: n20/D 1.432 (lit.); n20/D 1.433
• bp: 187 °C (lit.)
• mp: −60 °C (lit.)
• density: 1.036 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤1 mg/kg; sulfate (SO₄^2-): ≤20 mg/kg
• cation traces: Ca: ≤5 mg/kg; Cd: ≤1 mg/kg; Co: ≤1 mg/kg; Cr: ≤1 mg/kg; Cu: ≤1 mg/kg; Fe: ≤1 mg/kg; K: ≤20 mg/kg; Mg: ≤1 mg/kg; Mn: ≤1 mg/kg; Na: ≤20 mg/kg; Ni: ≤1 mg/kg; Pb: ≤1 mg/kg; Zn: ≤5 mg/kg
• SMILES string: CC(O)CO
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• InChI key: DNIAPMSPPWPWGF-UHFFFAOYSA-N

Description

General description

1,2-Propanediol is a 1,2-alkanediol. It can be obtained from glycerol, via hydrogenolysis in the presence of Ru/C and Amberlyst ion-exchange resins.

Application

1,2-Propanediol (propanediol) may be employed as a cryoprotective agent for the preservation (by cooling to sub-zero temperatures) of human embryos and oocytes (human and mouse).

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 219.2 °F - closed cup
• Flash Point(C): 104 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves