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49513

Supelco

Vitexin

analytical standard

Synonym(s):

4′,5,7-Trihydroxyflavone 8-C-glucoside, 8-C-Glucosylapigenin, Apigenin 8-C-glucoside, Orientoside

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About This Item

Empirical Formula (Hill Notation):
C21H20O10
CAS Number:
Molecular Weight:
432.38
Beilstein:
67796
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥95.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)cc4

InChI

1S/C21H20O10/c22-7-14-17(27)18(28)19(29)21(31-14)16-11(25)5-10(24)15-12(26)6-13(30-20(15)16)8-1-3-9(23)4-2-8/h1-6,14,17-19,21-25,27-29H,7H2/t14-,17-,18+,19-,21+/m1/s1

InChI key

SGEWCQFRYRRZDC-VPRICQMDSA-N

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General description

Vitexin is a naturally derived C-glycosylated flavone found in various medicinal plants which can exhibit a wide range of anti-tumor, anti-oxidative and anti-inflammatory properties.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Vitexin has been used as a standard in the determination of therapeutic potential of mung bean via inhibition of HMGB1, which in turn inhibits sepsis type of infection, using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: cannabis crataegus glycyrrhiza humulus

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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It is not just folklore: the aqueous extract of mung bean coat is protective against sepsis
Zhu S, et al.
BMC Complementary and Alternative Medicine, 2012 (2012)
It is not just folklore: the aqueous extract of mung bean coat is protective against sepsis
Zhu S, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2012 (2012)
Genotoxicity and Antigenotoxicity Assessments of the Flavonoid Vitexin by the Drosophila melanogaster Somatic Mutation and Recombination Test
Fernandes ML
Journal of Medicinal Food (2017)
Shaoli Zhang et al.
Molecular immunology, 85, 214-221 (2017-03-14)
Endothelial cell injury plays a crucial role in the development and pathogenesis of cardiovascular disease. Vitexin is a natural flavonoid characterized by anti-oxidative and anti-inflammatory properties. The purpose of this study was to investigate the effects of vitexin on ox-LDL-induced
Vitexin alleviates ox-LDL-mediated endothelial injury by inducing autophagy via AMPK signaling activation
Zhang S, et al.
Molecular Immunology, 85, 214-221 (2017)

Protocols

Effective analysis of passion flower by HPTLC fingerprinting, in conjunction with a comprehensive range of related reference materials, enables fast and efficient identification of this plant material.

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