Skip to Content
Merck
All Photos(1)

Key Documents

ABE295

Sigma-Aldrich

Anti-Zinc Finger Protein 260 Antibody

serum, from rabbit

Synonym(s):

Zinc finger protein 260, Zfp-260, Pancreas-only zinc finger protein 1, POZF-1

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, human

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_059060

UniProt accession no.

Q62981

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ZNF260(339324)

General description

Zinc finger protein 260 (PEX1) is transcription factor, which belongs to the krueppel C2H2-type zinc-finger protein family. It is expressed in fetal and adult heart, lung, skeletal muscle, and adrenal glands. It responds to changes in the activity of alpha1-adrenergic receptors; and binds to PE response elements in genes involved in cardiac function, such as ANF/NPPA.

Immunogen

MBP-tagged recombinant protein corresponding to rat Zinc Finger Protein 260.

Application

Detect Zinc Finger Protein 260 using this Anti-Zinc Finger Protein 260 Antibody validated for use in Western Blotting, ICC & IHC.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Zinc Finger Protein 260 in 10 µg of mouse heart tissue lysate.

Immunocytocchemistry Analysis: A representative lot from an independent laboratory detected Zinc Finger Protein 260 in adeno-HA-AS-PEX1-infected rat primary cardiomyocytes (Komati, H., et al. (2011). J Biol Chem. 286(2):1508-1516.).

Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Zinc Finger Protein 260 in alpha-MHCMerCreMer/CAT-PEX1 transgenic mouse heart tissue treated with Tamoxifen (Komati, H., et al. (2011). J Biol Chem. 286(2):1508-1516.).

Quality

Evaluated by Western Blot in human heart tissue lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Zinc Finger Protein 260 in 10 µg of human heart tissue lysate.

Target description

~46 kDa observed. An uncharacterized band may be observed at ~16 kDa in some cell lysates.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hiba Komati et al.
The Journal of biological chemistry, 286(2), 1508-1516 (2010-11-06)
Pressure and volume overload induce hypertrophic growth of postnatal cardiomyocytes and genetic reprogramming characterized by reactivation of a subset of fetal genes. Despite intense efforts, the nuclear effectors of cardiomyocyte hypertrophy remain incompletely defined. Endothelin-1 (ET-1) plays an important role

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service