All Photos(1)

Documents

N19702

2-Nitrophenol

Name: 2-Nitrophenol
Brand: ALDRICH

98%

Synonym(s):

2-Hydroxynitrobenzene, o-Hydroxynitrobenzene, o-Nitrophenol

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

Linear Formula:

O₂NC₆H₄OH

CAS Number:

88-75-5

Molecular Weight:

139.11

Beilstein:

775403

EC Number:

201-857-5

MDL number:

MFCD00011688

UNSPSC Code:

12352100

PubChem Substance ID:

24897541

NACRES:

NA.22

vapor pressure

1 mmHg ( 49.3 °C)

Assay

98%

form

needles

SMILES string

Oc1ccccc1[N+]([O-])=O

InChI

1S/C6H5NO3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H

InChI key

IQUPABOKLQSFBK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

2-Nitrophenol can be used in the iron-catalyzed synthesis of 2-arylbenzoxazole from benzylic alcohols.
It is employed in the preparation of heterodiazocines, which are potential photochromic compounds for applications in photopharmacology and functional materials.
It can be used as a precursor in synthesizing “off-on” chemosensor for Hg²⁺ detection in aqueous acetonitrile solution.
Additional application includes the synthesis of 1,4-benzoxazine derivative in the total synthesis of antimicrobial agent, levofloxacin.

Physical form

Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Pictograms

GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H410

Precautionary Statements

P261 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

212.9 °F - closed cup

Flash Point(C)

100.5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

Supelco

35836

4-Nitrophenol

USP

1056504

1,4-Benzoquinone

S682810

2-NITROPHENOL, SODIUM SALT

Supelco

1.06794

3-Nitrophenol

Sigma-Aldrich

8.20895

3-Nitrophenol

Heterodiazocines: Synthesis and Photochromic Properties, Trans to Cis Switching within the Bio-optical Window.

Hammerich M, et al.

Journal of the American Chemical Society, 138(40), 13111-13114 (2016)

Hg2+-selective ratiometric and ?Off? On? chemosensor based on the azadiene? pyrene derivative.

Zhou Y, et al.

Organic Letters, 12(11), 2566-2569 (2010)

Iron-catalyzed 2-arylbenzoxazole formation from o-nitrophenols and benzylic alcohols.

Wu M, et al.

Organic Letters, 14(11), 2722-2725 (2012)

Chemoenzymatic asymmetric synthesis of 1, 4-benzoxazine derivatives: Application in the synthesis of a levofloxacin precursor.

Lopez-Iglesias M, et al.

The Journal of Organic Chemistry, 80(8), 3815-3824 (2015)

Near-ultraviolet absorption cross sections of nitrophenols and their potential influence on tropospheric oxidation capacity.

Jun Chen et al.

The journal of physical chemistry. A, 115(44), 12235-12242 (2011-10-01)

Nitrophenols and methylnitrophenols have been identified as photolytic precursors of nitrous acid, HONO, but their gas-phase absorption has not previously been reported. In this study, the absorption cross sections of 2-nitrophenol, 3-methyl-2-nitrophenol, and 4-methyl-2-nitrophenol were measured from 320 to 450

View All Related Papers

Articles

US EPA Method 8041: GC Analysis of Phenols on Equity®-5

Separation of 2-Chlorophenol; 2,4-Dichlorophenol; 2,4,6-Tribromophenol; 2,4,6-Trichlorophenol; 2,4-Dinitrophenol; Pentafluorophenol; 2-Methylphenol, analytical standard; 2,3,4,6-Tetrachlorophenol; Pentachlorophenol; 4-Nitrophenol; 2-Bromophenol; 2,3,5,6-Tetrachlorophenol; 2,3,5-Trichlorophenol; 4-Chloro-3-methylphenol; 2,4,5-Trichlorophenol; 4-Methylphenol, analytical standard; 2,4-Dimethylphenol; 2-Nitrophenol; 3-Methylphenol, analytical standard; Phenol; 2-Methyl-4,6-dinitrophenol; 2,3,4-Trichlorophenol; 2,6-Dichlorophenol; 2,3,4,5-Tetrachlorophenol

Protocols

GC Analysis of Phenols in Water on a 5% Phenyl Column after SPE using Supelclean™ ENVI-Chrom P

Separation of 2-Nitrophenol; Pentachlorophenol; 2-Bromophenol; Phenol; 4-Nitrophenol; 3-Methylphenol, analytical standard; 4-Chloro-3-methylphenol; 2,4-Dichlorophenol; 2,3,4,6-Tetrachlorophenol; 2-Methylphenol, analytical standard; 2,4,6-Trichlorophenol; 2,4-Dimethylphenol; 2-Chlorophenol

HPLC Analysis of Phenols on SUPELCOSIL™ LC-8

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service