923478

CyMPhos

• Synonym(s): 1-Diadamantylphosphino-1′-dicyclohexylphosphinoferrocene
• Empirical Formula (Hill Notation): C₄₂H₆₀FeP₂
• Molecular Weight: 682.72
• NACRES: NA.21

Properties

• reaction suitability: reagent type: catalyst; reaction type: Cross Couplings; reagent type: ligand
• Quality Level: 100
• functional group: phosphine
• SMILES string: c1(P(C2CCCCC2)C3CCCCC3)cccc1.c4(P([C@@]56C[C@@H](C[C@H]7C6)C[C@@H](C7)C5)[C@@]89C[C@@H](C[C@H]%10C9)C[C@@H](C%10)C8)cccc4.[Fe]

Description

Application

CyMPhos is an unsymmetrical ferrocene-based phosphine ligand. The MPhos series of ligands are unsymmetrical diphosphino-ferrocenes bearing a bulky adamantyl group. Pd catalysts containing CyMPhos can be used for a variety of cross-coupling transformations, including Suzuki coupling, C-P coupling, and Csp²-Csp³ coupling. Demonstrated Csp²-Csp³ couplings include Murahashi-Feringa Coupling (Alkyl-Li), Kumada-Corriu coupling (Alkyl-MgX), Negishi coupling (Alkyl-ZnX) and Suzuki–Miyaura coupling (Alkyl-B(OR2)).

Learn more about MPhos ligands and catalysts

Other Notes

Tunable Unsymmetrical Ferrocene Ligands Bearing a Bulky Di-1-adamantylphosphino Motif for Many Kinds of Csp²–Csp³ Couplings

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable