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700304

Sigma-Aldrich

Iron oxide(II,III), magnetic nanoparticles solution

20 nm avg. part. size, 5 mg/mL in toluene

Synonym(s):

Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles

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About This Item

Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
Molecular Weight:
231.53
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23

form

nanoparticles
solution

Quality Level

concentration

5 mg/mL in toluene

magnetization

>20 emu/g, at room temp. under 4500 Oe

avg. part. size

20 nm

particle size

20 nm (+/- 2nm TEM)

density

0.865 g/mL at 25 °C

SMILES string

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

InChI key

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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General description

Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

45.0 °F

Flash Point(C)

7.2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jens Baumgartner et al.
Nature materials, 12(4), 310-314 (2013-02-05)
The formation of crystalline materials from solution is usually described by the nucleation and growth theory, where atoms or molecules are assumed to assemble directly from solution. For numerous systems, the formation of the thermodynamically stable crystalline phase is additionally
Marina I Siponen et al.
Nature, 502(7473), 681-684 (2013-10-08)
Magnetotactic bacteria align along the Earth's magnetic field using an organelle called the magnetosome, a biomineralized magnetite (Fe(II)Fe(III)2O4) or greigite (Fe(II)Fe(III)2S4) crystal embedded in a lipid vesicle. Although the need for both iron(II) and iron(III) is clear, little is known
Maoquan Chu et al.
Biomaterials, 34(16), 4078-4088 (2013-03-08)
The photothermal effect of Fe3O4 magnetic nanoparticles is investigated for cancer therapy both in vitro and in vivo experiments. Heat is found to be rapidly generated by red and near-infrared (NIR) range laser irradiation of Fe3O4 nanoparticles with spherical, hexagonal and wire-like
A Aranda et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 954-963 (2013-01-30)
No consensus exists on how to address possible toxicity of nanomaterials as they interfere with most in vitro screening tests based on colorimetric and fluorimetric probes such as the dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay for detection of oxidative species. In the
Tsung-Ju Li et al.
Biomaterials, 34(32), 7873-7883 (2013-07-24)
We present an approach for synchronizing hyperthermia and thermal-responsive local drug release. The targeting probe has a magnetite nanocrystal (Fe₃O₄@PSMA) core and a polynucleotide shell that carries 5-fluorouracil (5-FU) and anti-human epidermal growth factor receptor 2 (anti-HER2) antibody for cancer

Articles

A key challenge for nanomaterial safety assessment is the ability to handle the large number of newly engineered nanomaterials (ENMs), including developing cost-effective methods that can be used for hazard screening.

Graphene is a unique two-dimensional (2D) structure of monolayer carbon atoms packed into a dense honeycomb crystal that has attracted great interest due to its diverse and fascinating properties.

Professor Hui Mao explores the use of superparamagnetic iron oxide nanoparticles (INOPs) that offer an alternate contrast-enhancing mechanism.

Professor Yadong Yin (University of California Riverside, USA) examines both direct (thermal decomposition, solvothermal, hydrothermal) and indirect (templated) synthesis methods of magnetite nanocrystals and reviews in detail the landscape of these various synthetic methods for magnetite nanocrystal and their applications in magnetic assembly, magnetic hyperthermia, and Li-Ion batteries.

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