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655651

Sigma-Aldrich

Dopamine-1,1,2,2-d4 hydrochloride

98 atom % D

Synonym(s):

2-(3,4-Dihydroxyphenyl)ethyl-1,1,2,2-d4-amine hydrochloride

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About This Item

Linear Formula:
C8D4H7O2N.HCl
CAS Number:
203633-19-6
Molecular Weight:
193.66
MDL number:
MFCD01317352
UNSPSC Code:
12352116
PubChem Substance ID:
329760079
NACRES:
NA.12

isotopic purity

98 atom % D

Quality Level

200

Assay

99% (CP)

form

solid

mp

248-250 °C (lit.)

mass shift

M+4

SMILES string

Cl.[2H]C([2H])(N)C([2H])([2H])c1ccc(O)c(O)c1

InChI

1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H/i3D2,4D2;

InChI key

CTENFNNZBMHDDG-URZLSVTISA-N

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Packaging

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD3234
MBBB9876V
MBBB6986V
MBBB4850V
MBBB4399V

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Finasteride, a 5-alpha reductase (5α-R) inhibitor, is a widely used drug for treating androgen-dependent conditions. However, its use is associated with sexual, psychological, and physical complaints, suggesting that other mechanisms, in addition to 5α-R inhibition, may be involved. Here, a
Kate Thomson et al.
Experimental eye research, 200, 108233-108233 (2020-09-14)
Animal models have demonstrated a link between dysregulation of the retinal dopamine system and the development of experimental myopia (short-sightedness). However, pharmacological investigations of dopamine in animal models rely heavily on intravitreal or systemic administration, which have several limitations for

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