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484423

Sigma-Aldrich

1-Phenoxy-2-propanol

≥93%

Synonym(s):

DOWANOL® PPh, Propylene glycol phenyl ether, Propylene phenoxytol

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About This Item

Linear Formula:
C6H5OCH2CH(OH)CH3
CAS Number:
770-35-4
Molecular Weight:
152.19
Beilstein:
1941356
EC Number:
212-222-7
MDL number:
MFCD00016861
UNSPSC Code:
12352112
PubChem Substance ID:
24871949
NACRES:
NA.21

Quality Level

100

Assay

≥93%

impurities

<7% di(propylene glycol) phenyl ether

refractive index

n20/D 1.523 (lit.)

bp

243 °C (lit.)

solubility

water: soluble 198 g/L at 20 °C

density

1.064 g/mL at 20 °C (lit.)

SMILES string

CC(O)COc1ccccc1

InChI

1S/C9H12O2/c1-8(10)7-11-9-5-3-2-4-6-9/h2-6,8,10H,7H2,1H3

InChI key

IBLKWZIFZMJLFL-UHFFFAOYSA-N

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General description

1-Phenoxy-2-propanol (PP), a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3-MgO/Fe3O4 catalyst. The influence of its anesthetic property on gastropods has been analyzed. Its degradation by microorganisms in different soil types has been investigated.

Application

1-Phenoxy-2-propanol has been used as an additive to saline to induce anesthetic effect on the peripheral tissues isolated from Biomphalaria alexandrina prior to fixation.

Legal Information

DOWANOL is a registered trademark of The Dow Chemical Company or an affiliated company of Dow

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Oded Halevi et al.
Scientific reports, 6, 36786-36786 (2016-11-11)
We present an all-additive manufacturing method that is performed at mild conditions, for the formation of organic single crystals at specific locations, without any photolithography prefabrication process. The method is composed of two steps; inkjet printing of a confinement frame
A Magnetically Separable Catalyst for Synthesis of 1-Phenoxy-2-propanol Via Atom-economic Reaction.
Feng S, et al.
J. Chin. Chem. Soc., 61(10), 1084-1088 (2014)
I K Hegna et al.
Annales de l'Institut Pasteur. Microbiology, 139(4), 473-483 (1988-07-01)
The bactericidal and fungicidal effects of five disinfectants and one combination of two disinfectants were tested using a modified Kelsey-Sykes method in which living microorganisms suspended in a sterilized yeast suspension ("dirty" conditions) and in sterile distilled water ("clean" conditions)
J Greenman
Microbios, 39(156), 101-108 (1984-01-01)
Propionibacterium acnes was grown in continuous culture in the presence of propylene phenoxetol. At sub-lethal concentrations of this antimicrobial agent (0.025-0.1% w/v) steady-state growth conditions were achieved. In comparison with the control, cell biomass, maximum specific growth rates and levels
Russell C Wyeth et al.
Journal of neuroscience methods, 176(2), 121-128 (2008-09-24)
Anaesthesia is often used in neurophysiological, surgical, and neuroanatomical protocols. Several anaesthetics, including magnesium chloride, volatiles (halothane, etc.), and barbiturates, have been used in gastropod neurobiology. 1-Phenoxy-2-propanol (PP) is another anaesthetic option that has not yet been used extensively. We
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