365815

4-(Trifluoromethyl)benzyl chloride

98%

• Synonym(s): α′-Chloro-α,α,α-trifluoro-p-xylene
• Linear Formula: CF₃C₆H₄CH₂Cl
• CAS Number: 939-99-1
• Molecular Weight: 194.58
• MDL number: MFCD00040772
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862581
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.464 (lit.)
• bp: 68 °C/12 mmHg (lit.)
• density: 1.315 g/mL at 25 °C (lit.)
• SMILES string: FC(F)(F)c1ccc(CCl)cc1
• InChI: 1S/C8H6ClF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2
• InChI key: MCHDHQVROPEJJT-UHFFFAOYSA-N

Description

General description

Electrochemical reduction of 4-(trifluoromethyl)benzyl chloride catalyzed by Co(salen) (H₂salen, N,N′-bis(salicylidene)-ethane-1,2-diamine) in acetonitrile is reported.

Application

4-(Trifluoromethyl)benzyl chloride may be used in the synthesis of novel series of dithiocarbamates, via reaction with sodium salts of N,N-disubstituted dithiocarbamic acids.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H314,H335
• Precautionary Statements: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 165.2 °F - closed cup
• Flash Point(C): 74 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves