362883

Dibenzyl N,N-diethylphosphoramidite

technical grade, 85%

• Synonym(s): TTC
• Linear Formula: (C₂H₅)₂NP(OCH₂C₆H₅)₂
• CAS Number: 67746-43-4
• Molecular Weight: 317.36
• Beilstein: 4189915
• MDL number: MFCD00191987
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862337
• NACRES: NA.22

Properties

• grade: technical grade
• vapor pressure: 0.71 psi ( 55 °C)
• Assay: 85%
• form: liquid
• refractive index: n20/D 1.545 (lit.)
• density: 1.06 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CCN(CC)P(OCc1ccccc1)OCc2ccccc2
• InChI: 1S/C18H24NO2P/c1-3-19(4-2)22(20-15-17-11-7-5-8-12-17)21-16-18-13-9-6-10-14-18/h5-14H,3-4,15-16H2,1-2H3
• InChI key: NLGUJOVLAXLSMX-UHFFFAOYSA-N

Description

General description

Dibenzyl N,N-diethylphosphoramidite is repoted to be suitable reagent for the efficient 1H-tetrazole-catalyzed ′phosphite-triester′ phosphorylation of the protected serine derivatives.

Application

Dibenzyl N,N-diethylphosphoramidite may be used:

• as phosphitylating reagent in the synthesis of glycosyl phosphites and phosphates
• for phosphorylating the alcohols
• in the preparation of 6-dibenzylphosphate-1,3,5-tri-O-PMB-myo-inositol

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 93.2 °F - closed cup
• Flash Point(C): 34 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves