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Key Documents

223220

Sigma-Aldrich

Thiocarbohydrazide

98%

Synonym(s):

Thiocarbonyldihydrazide

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About This Item

Linear Formula:
(NH2NH)2CS
CAS Number:
Molecular Weight:
106.15
Beilstein:
506657
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39093513
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

mp

171-174 °C (dec.) (lit.)

functional group

amine
hydrazine
thiourea

SMILES string

NNC(=S)NN

InChI

1S/CH6N4S/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

InChI key

LJTFFORYSFGNCT-UHFFFAOYSA-N

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Application


  • Review of transition metal complexes with thiocarbohydrazides: This comprehensive review discusses the coordination chemistry of thiocarbohydrazides with various metals, highlighting their relevance in the synthesis of complex metal compounds used in catalysis and pharmaceutical research (Aly et al., 2023).

  • Pd-doped nanocomposites for organometallic catalysis: Thiocarbohydrazide was employed in the fabrication of Pd-doped SBA-15 nanocomposites, applied as catalysts in the synthesis of organometallic compounds, showcasing its utility as a catalyst support material (Kalhor and Dadras, 2021).

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M A Badawy et al.
Archiv der Pharmazie, 324(6), 349-351 (1991-06-01)
Heterocycles containing the indole ring system include some novel pharmacologically active compounds. Isatin and its N-acetylisatin are extremely versatile intermediates in the construction of a variety of heterocyclic systems when reacted with thiosemicarbazide derivatives. Literature survey revealed various interesting reactions
E A Dunnebier et al.
Hearing research, 90(1-2), 139-148 (1995-10-01)
The stereociliar structures of the guinea-pig cochlear organ of Corti were studied at low-voltage (1-5 kV) with field-emission scanning electron microscope (SEM) using various pre- and post-fixation methods, such as OTOTO (OsO4/thiocrbohydrazide/OsO4/thiocarbohydrazide/OsO4) and TAO (tannic acid/arginine/OsO4), and different dissection procedures
D P Singh et al.
Journal of enzyme inhibition and medicinal chemistry, 22(2), 177-182 (2007-05-24)
A novel series of complexes of the type [M(TML)X2]; where TML is Tetradentate Macrocyclic Ligand; M = Co(II), Ni(II), Cu(II), Zn(II)or Cd(II); X = Cl-, CH3COO- or NO3- have been synthesized by template condensation of glyoxal and thiocarbohydrazide in the
D Levanon et al.
The Histochemical journal, 31(1), 71-73 (1999-07-16)
Samples from seven sectors of the rabbit knee articular cartilage were shaved and prepared for the scanning electron microscope using either tannic acid, thiocarbohydrazide or nothing (control). Surface morphology was found to be more typical to a given sector and
Kamaleddin Haj Mohammad Ebrahim Tehrani et al.
Iranian journal of pharmaceutical research : IJPR, 12(2), 331-346 (2013-11-20)
In this work, we reported the synthesis and evaluation of antimycobacterial and antifungal activity of a series of thiocarbohydrazone derivatives which are thiacetazone congeners. The target compounds were synthesized in superior yields by reacting thiocarbohydrazide with different aromatic aldehydes and

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