172472
Isopropyl myristate
98%
Synonym(s):
Isopropyl tetradecanoate, Myristic acid isopropyl ester
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About This Item
Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
Molecular Weight:
270.45
Beilstein:
1781127
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39022421
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
liquid
refractive index
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
density
0.85 g/mL at 25 °C (lit.)
SMILES string
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
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General description
IPM is a fatty acid ester that can be produced by the esterification of isopropyl alcohol and myristic acid.
Application
Isopropyl myristate was used as oil phase in the preparation of formulations. It was also used as oil/water-type tacrolimus (FK506) solvent.
Storage Class Code
10 - Combustible liquids
WGK
awg
Flash Point(F)
>302.0 °F
Flash Point(C)
> 150 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
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To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
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